Anderson County is a county located in the U.S. state of South Carolina. As of the 2020 census, its population was 203,718. Its county seat is Anderson. Named for Revolutionary War leader Robert Anderson, the county is located in northwestern South Carolina, along the state line of Georgia. Anderson County is included in the Greenville-Anderson-Greer, SC Metropolitan Statistical Area. Anderson County contains 55,950-acre (22,640 ha) Lake Hartwell, a U.S. Army Corps of Engineers lake with nearly 1,000 miles (1,600 km) of shoreline for residential and recreational use. The area is a growing industrial, commercial and tourist center. It is the home of Anderson University, a private, selective comprehensive university of approximately 4,000 undergraduate and graduate students.

Anderson is a city in and the county seat of Anderson County, South Carolina, United States. The population was 28,106 at the 2020 census, making it the 16th-most populous city in South Carolina. It is one of the principal cities in the Greenville-Anderson-Greer, SC Metropolitan Statistical Area, which had an estimated population of 975,480 in 2023. It is included in the larger Greenville-Spartanburg-Anderson, SC Combined Statistical Area, which had an estimated population of 1,590,636 in 2023. It is just off Interstate 85 and is 120 miles (190 km) from Atlanta and 140 miles (230 km) from Charlotte. Anderson is the smallest of the three primary cities that make up the Upstate region, and is nicknamed the "Electric City" and the "Friendliest City in South Carolina".