Anson County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 22,055. Its county seat is Wadesboro.

Wadesboro is a town and the county seat of Anson County, North Carolina, United States. The population was 5,008 at the 2020 census. The town was originally found in 1783 as New Town but changed by the North Carolina General Assembly to Wadesboro in 1787 to honor Colonel Thomas Wade, a native son, state legislator, and Revolutionary War commander of the Anson County Regiment.