The Commander-in-Chief South Atlantic was an operational commander of the Royal Navy from 1939. The South American area was added to his responsibilities in 1960, and the post disestablished in 1967.

The Commander-in-Chief, Africa was the last title of a Royal Navy's formation commander located in South Africa from 1795 to 1939. Under varying titles, it was one of the longest-lived formations of the Royal Navy. It was also often known as the Cape of Good Hope Station.