There are over 20,000 Grade II* listed buildings in England. This page is a list of these buildings in the county of Merseyside.

Knowsley Hall is a stately home near Liverpool in the Metropolitan Borough of Knowsley, Merseyside, England. It is the ancestral home of the Stanley family, the Earls of Derby. The hall is surrounded by 2,500 acres (10 km2) of parkland, which contains the Knowsley Safari Park. Though the hall is still owned by the Stanley family, it is no longer a family home, but is instead used for corporate events, conferences and weddings. Since 1953, it has been designated a Grade II* listed building.