Greene County is a county located in the east central portion & the Lake country region of the U.S. state of Georgia. As of the 2020 census, the population was 18,915. The county seat is Greensboro. The county was created on February 3, 1786, and is named for Nathanael Greene, an American Revolutionary War major general.

Greensboro is a city in and the county seat of Greene County, Georgia, United States. Its population was 3,648 as of the 2020 census. The city is located approximately halfway between Atlanta and Augusta on Interstate 20.