House is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. Its main character, Dr. Gregory House, is an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for conceiving the title character.

Gregory House is a fictional character and the titular protagonist of the American medical drama series House. Created by David Shore and portrayed by English actor Hugh Laurie, he leads a team of diagnosticians and is the Head of Diagnostic Medicine at the fictional Princeton-Plainsboro Teaching Hospital in Princeton, New Jersey. House's character has been described as a misanthrope, cynic, narcissist, and curmudgeon, the last of which terms was named one of the top television words of 2005 in honor of the character.