John Spencer was an English politician who sat in the House of Commons from 1732 to 1746.

Charles Spencer, 3rd Earl of Sunderland, KG, PC, known as Lord Spencer from 1688 to 1702, was an English statesman and nobleman from the Spencer family. He served as Lord Lieutenant of Ireland (1714–1717), Lord Privy Seal (1715–1716), Lord President of the Council (1718–1719) and First Lord of the Treasury (1718–1721).