Little Germany, known in German as Kleindeutschland and Deutschländle and called Dutchtown by contemporary non-Germans, was a German immigrant neighborhood on the Lower East Side and East Village neighborhoods of Manhattan in New York City. The demography of the neighborhood began to change in the late 19th century, as non-German immigrants settled in the area. A steady decline of Germans among the population was accelerated in 1904, when the General Slocum disaster decimated the social core of the population with the loss of more than 1,000 lives.

The Lower East Side, sometimes abbreviated as LES, is a historic neighborhood in the southeastern part of Manhattan in New York City. It is located roughly between the Bowery and the East River from Canal to Houston streets. Historically, it was understood to encompass a much larger area, from Broadway to the East River and from East 14th Street to Fulton and Franklin Streets.