Rampage is a 2018 American science fiction monster film directed by Brad Peyton and loosely based on the video game series of the same name by Midway Games, from a screenplay by Ryan Engle, Carlton Cuse, Ryan J. Condal and Adam Sztykiel. The film stars Dwayne Johnson in the lead role, Naomie Harris, Malin Åkerman, Jake Lacy, Joe Manganiello and Jeffrey Dean Morgan. It follows a primatologist who must team up with George, an albino western lowland gorilla who turns into a raging creature of enormous size and growing into bigger and larger sizes as a result of a rogue experiment, to stop two other mutated animals from destroying Chicago.

Arthur Carlton Cuse, known as Carlton Cuse, is an American screenwriter, showrunner, producer, and director, best known for the American television series Lost, for which he made the Time list of the 100 most influential people in the world in 2010.