The Shenandoah was a daily passenger train operated by Amtrak between Washington and Cincinnati from 1976 until 1981.

The Shenandoah was an American named passenger train of the Baltimore and Ohio Railroad (B&O), one of four daily B&O trains operating between Jersey City, New Jersey and Grand Central Station in Chicago, Illinois, via Washington, D.C., and Pittsburgh, Pennsylvania from the 1930s to the 1950s. Other B&O trains of that period on the route were the Capitol Limited, Columbian, and the Washington–Chicago Express. An alternate branch originated in Detroit and met with the Chicago part of the train at Deshler, Ohio, south of Toledo.