The Motorcycle Diaries is a 2004 biopic about the journey and written memoir of the 23-year-old Ernesto Guevara, who would several years later become internationally known as the Marxist guerrilla leader and revolutionary leader Che Guevara. The film recounts the 1952 expedition, initially by motorcycle, across South America by Guevara and his friend Alberto Granado. As well as being a road movie, the film is a coming-of-age film; as the adventure, initially centered on youthful hedonism, unfolds, Guevara discovers himself transformed by his observations on the life of the impoverished indigenous peasantry. Through the characters they encounter on their continental trek, Guevara and Granado witness first hand the injustices that the destitute face and are exposed to people and social classes they would have never encountered otherwise. To their surprise, the road presents to them both a genuine and captivating picture of Latin American identity. As a result, the trip also plants the initial seed of radicalization within Guevara, who would later challenge the continent's endemic economic inequalities and political repression.

Ernesto "Che" Guevara was an Argentine Marxist revolutionary, physician, author, guerrilla leader, diplomat, and military theorist. A major figure of the Cuban Revolution, his stylized visage has become a ubiquitous countercultural symbol of rebellion and global insignia in popular culture.