The third USS Columbus (CA-74/CG-12), a Baltimore-class heavy cruiser, was the first ship of the United States Navy named for Columbus, Ohio. She was launched on 30 November 1944 by Bethlehem Steel Co., Quincy, Massachusetts; she was sponsored by Mrs. E. G. Meyers; and commissioned on 8 June 1945.

The Baltimore-class heavy cruisers were a class of heavy cruisers in the United States Navy commissioned during and shortly after World War II. Fourteen Baltimores were completed, more than any other class of heavy cruiser, along with another three ships of the Oregon City sub-class. The Baltimores also were the first cruisers in the US Navy to be designed without the limitations of the London Naval Treaty.