Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase

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cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
Identifiers
EC number 1.3.1.49
CAS number 118390-61-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49) is an enzyme that catalyzes the chemical reaction

(+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ phenanthrene-3,4-diol + NADH + H+

Thus, the two substrates of this enzyme are (+)-cis-3,4-dihydrophenanthrene-3,4-diol and NAD+, whereas its 3 products are phenanthrene-3,4-diol, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor, the systematic name of this enzyme class is (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

References[edit]

  • Nagao K, Takizawa N, Kiyahara H (1988). "Purification and properties of cis-phenanthrene dihydrodiol dehydrogenase in Alcaligenes faecalis AFK2". Agric. Biol. Chem. 52 (10): 2621–2623. doi:10.1271/bbb1961.52.2621.