(-)-Isopiperitenone reductase

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(-)-isopiperitenone reductase
Identifiers
EC number 1.3.1.82
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(-)-Isopiperitenone reductase (EC 1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

(+)-cis-isopulegone + NADP+ (-)-isopiperitenone + NADPH + H+

The reaction occurs in the opposite direction.

References[edit]

  1. ^ Croteau, R.; Venkatachalam, K.V. (1986). "Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita)". Arch. Biochem. Biophys. 249: 306–315. doi:10.1016/0003-9861(86)90007-x. PMID 3755881. 
  2. ^ Ringer, K.L.; McConkey, M.E.; Davis, E.M.; Rushing, G.W.; Croteau, R. (2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Arch. Biochem. Biophys. 418: 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086. 

External links[edit]