(+)-sativene synthase

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(+)-sativene synthase
Identifiers
EC number 4.2.3.129
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(+)-sativene synthase (EC 4.2.3.129, cop4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-sativene-forming).[1][2][3] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-sativene + diphosphate

This enzyme is isolated from the fungus Coprinus cinereus.

References[edit]

  1. ^ Agger, S.; Lopez-Gallego, F.; Schmidt-Dannert, C. (2009). "Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus". Mol. Microbiol. 72: 1181–1195. doi:10.1111/j.1365-2958.2009.06717.x. PMC 2723806Freely accessible. PMID 19400802. 
  2. ^ Lopez-Gallego, F.; Agger, S.A.; Abate-Pella, D.; Distefano, M.D.; Schmidt-Dannert, C. (2010). "Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers". Chembiochem. 11: 1093–1106. doi:10.1002/cbic.200900671. PMC 2873112Freely accessible. PMID 20419721. 
  3. ^ Lopez-Gallego, F.; Wawrzyn, G.T.; Schmidt-Dannert, C. (2010). "Selectivity of fungal sesquiterpene synthases: role of the active site’s H-1α loop in catalysis". Appl. Environ. Microbiol. 76: 7723–7733. doi:10.1128/aem.01811-10. PMC 2988597Freely accessible. PMID 20889795. 

External links[edit]