(-)-alpha-cuprenene synthase

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(-)-alpha-cuprenene synthase
Identifiers
EC number 4.2.3.95
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(-)-alpha-cuprenene synthase (EC 4.2.3.95, Cop6) is an enzyme with systematic name (-)-alpha-cuprenene hydrolase (cyclizing, (-)-alpha-cuprenene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (-)-alpha-cuprenene + diphosphate

The enzyme from the fungus Coprinopsis cinerea produces (-)-alpha-cuprenene with high selectivity.

References[edit]

  1. ^ Lopez-Gallego, F.; Agger, S.A.; Abate-Pella, D.; Distefano, M.D.; Schmidt-Dannert, C. (2010). "Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers". Chembiochem. 11: 1093–1106. doi:10.1002/cbic.200900671. PMC 2873112Freely accessible. PMID 20419721. 

External links[edit]