(-)-camphene synthase

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(-)-camphene synthase
EC number
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(-)-camphene synthase (EC, CS) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (-)-camphene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

geranyl diphosphate (-)-camphene + diphosphate

(-)-Camphene is the major product in Abies grandis (grand fir) with traces of other monoterpenoids.


  1. ^ Bohlmann, J.; Phillips, M.; Ramachandiran, V.; Katoh, S.; Croteau, R. (1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Arch. Biochem. Biophys. 368: 232–243. doi:10.1006/abbi.1999.1332. PMID 10441373. 
  2. ^ Huber, D.P.W.; Philippe, R.N.; Godard, K.-A.; Sturrock, R.N.; Bohlmann, J. (2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66: 1427–1439. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711. 
  3. ^ Hyatt, D.C.; Croteau, R. (2005). "Mutational analysis of a monoterpene synthase reaction: altered catalysis through directed mutagenesis of (-)-pinene synthase from Abies grandis". Arch. Biochem. Biophys. 439: 222–233. doi:10.1016/j.abb.2005.05.017. PMID 15978541. 
  4. ^ Falara, V.; Akhtar, T.A.; Nguyen, T.T.; Spyropoulou, E.A.; Bleeker, P.M.; Schauvinhold, I.; Matsuba, Y.; Bonini, M.E.; Schilmiller, A.L.; Last, R.L.; Schuurink, R.C.; Pichersky, E. (2011). "The tomato terpene synthase gene family". Plant Physiol. 157 (2): 770–789. doi:10.1104/pp.111.179648. PMC 3192577Freely accessible. PMID 21813655. 

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