Ephedrine dehydrogenase

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ephedrine dehydrogenase
Identifiers
EC number 1.5.1.18
CAS number 73508-06-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an ephedrine dehydrogenase (EC 1.5.1.18) is an enzyme that catalyzes the chemical reaction

(-)-ephedrine + NAD+ (R)-2-methylimino-1-phenylpropan-1-ol + NADH + H+

Thus, the two substrates of this enzyme are (-)-ephedrine and NAD+, whereas its 3 products are (R)-2-methylimino-1-phenylpropan-1-ol, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor, the systematic name of this enzyme class is (-)-ephedrine:NAD+ 2-oxidoreductase.

References[edit]

  • Klamann E, Lingens F (1980). "Degradation of (-)-ephedrine by Pseudomonas putida. Detection of (-)-ephedrine: NAD+-oxidoreductase from Arthrobacter globiformis". Z. Naturforsch. C. 35 (1–2): 80–7. PMID 7405363.