Cis-abienol synthase

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Cis-abienol synthase
Identifiers
EC number 4.2.3.140
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cis-abienol synthase (EC 4.2.3.140, Z-abienol synthase, CAS, ABS) is an enzyme with systematic name (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming).[1][2] This enzyme catalyses the following chemical reaction

(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate cis-abienol + diphosphate

This enzyme is isolated from the plants Abies balsamea (balsam fir) and Nicotiana tabacum (tobacco).

References[edit]

  1. ^ Zerbe, P.; Chiang, A.; Yuen, M.; Hamberger, B.; Hamberger, B.; Draper, J.A.; Britton, R.; Bohlmann, J. (2012). "Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production". J. Biol. Chem. 287: 12121–12131. doi:10.1074/jbc.m111.317669. PMC 3320957Freely accessible. PMID 22337889. 
  2. ^ Sallaud, C.; Giacalone, C.; Topfer, R.; Goepfert, S.; Bakaher, N.; Rosti, S.; Tissier, A. (2012). "Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes". Plant J. 72: 1–17. doi:10.1111/j.1365-313x.2012.05068.x. PMID 22672125. 

External links[edit]