Germacrene-A synthase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Germacrene-A synthase
Identifiers
EC number 4.2.3.23
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a germacrene-A synthase (EC 4.2.3.23) is an enzyme that catalyzes the chemical reaction

2-trans,6-trans-farnesyl diphosphate (+)-(R)-gemacrene A + diphosphate

Hence, this enzyme has one substrate, 2-trans,6-trans-farnesyl diphosphate, and two products, (+)-(R)-gemacrene A and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates, the systematic name of this enzyme class is 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-(R)-germacrene-A-forming]. Other names in common use include germacrene A synthase, (+)-germacrene A synthase, (+)-(10R)-germacrene A synthase, GAS, 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase, and (germacrene-A-forming).

References[edit]