(+)-delta-selinene synthase

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(+)-delta-selinene synthase
Identifiers
EC number 4.2.3.76
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(+)-delta-selinene synthase (EC 4.2.3.76) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-delta-selinene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-delta-selinene + diphosphate

Initial cyclization gives germacrene C in an enzyme bound form.

References[edit]

  1. ^ Steele, C.L.; Crock, J.; Bohlmann, J.; Croteau, R. (1998). "Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase". J. Biol. Chem. 273: 2078–2089. doi:10.1074/jbc.273.4.2078. PMID 9442047. 
  2. ^ Little, D.B.; Croteau, R.B. (2002). "Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase". Arch. Biochem. Biophys. 402: 120–135. doi:10.1016/S0003-9861(02)00068-1. PMID 12051690. 

External links[edit]