Bicyclogermacrene synthase

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Bicyclogermacrene synthase
Identifiers
EC number 4.2.3.100
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Bicyclogermacrene synthase (EC 4.2.3.100, Ov-TPS4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate bicyclogermacrene + diphosphate

The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor.

References[edit]

  1. ^ Crocoll, C.; Asbach, J.; Novak, J.; Gershenzon, J.; Degenhardt, J. (2010). "Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis". Plant Mol. Biol. 73: 587–603. doi:10.1007/s11103-010-9636-1. PMID 20419468. 

External links[edit]