Cis-muuroladiene synthase

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Cis-muuroladiene synthase
Identifiers
EC number 4.2.3.67
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cis-muuroladiene synthase (EC 4.2.3.67, MxpSS1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming).[1] This enzyme catalyses the following chemical reaction

(1) (2E,6E)-farnesyl diphosphate cis-muurola-3,5-diene + diphosphate
(2) (2E,6E)-farnesyl diphosphate cis-muurola-4(14),5-diene + diphosphate

The recombinant enzyme from black peppermint produces a mixture of cis-muurola-3,5-diene and cis-muurola-4(14),5-diene.

References[edit]

  1. ^ Prosser, I.M.; Adams, R.J.; Beale, M.H.; Hawkins, N.D.; Phillips, A.L.; Pickett, J.A.; Field, L.M. (2006). "Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Mentha × piperita) and direct evidence for a chemotype unable to synthesise farnesene". Phytochemistry. 67: 1564–1571. doi:10.1016/j.phytochem.2005.06.012. PMID 16083926. 

External links[edit]