(+)-T-muurolol synthase

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(+)-T-muurolol synthase
Identifiers
EC number 4.2.3.98
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(+)-T-muurolol synthase (EC 4.2.3.98) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-T-muurolol-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O (+)-T-muurolol + diphosphate

The cyclization mechanism involves an intermediate nerolidyl diphosphate.

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