Presilphiperfolanol synthase

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Presilphiperfolanol synthase
Identifiers
EC number 4.2.3.74
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Presilphiperfolanol synthase (EC 4.2.3.74, BcBOT2, CND15) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase (presilphiperfolan-8beta-ol-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O presilphiperfolan-8beta-ol + diphosphate

This enzyme requires Mg2+.

References[edit]

  1. ^ Pinedo C, Wang CM, Pradier JM, Dalmais B, Choquer M, Le Pêcheur P, Morgant G, Collado IG, Cane DE, Viaud M (2008). "Sesquiterpene synthase from the botrydial biosynthetic gene cluster of the phytopathogen Botrytis cinerea". ACS Chem. Biol. 3: 791–801. doi:10.1021/cb800225v. PMC 2707148Freely accessible. PMID 19035644. 
  2. ^ Wang CM, Hopson R, Lin X, Cane DE (2009). "Biosynthesis of the sesquiterpene botrydial in Botrytis cinerea. Mechanism and stereochemistry of the enzymatic formation of presilphiperfolan-8beta-ol". J. Am. Chem. Soc. 131 (24): 8360–1. doi:10.1021/ja9021649. PMC 2702122Freely accessible. PMID 19476353. 

External links[edit]