(2R)-3-sulfolactate dehydrogenase (NADP+)

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(2R)-3-sulfolactate dehydrogenase (NADP+)
Identifiers
EC number 1.1.1.338
CAS number 81210-65-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(2R)-3-sulfolactate dehydrogenase (NADP+) (EC 1.1.1.338, (R)-sulfolactate:NADP+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenase, ComC) is an enzyme with systematic name (2R)-3-sulfolactate:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

(2R)-3-sulfolactate + NADP+ 3-sulfopyruvate + NADPH + H+

The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+.

References[edit]

  1. ^ Denger, K.; Cook, A. M. (2010). "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase". Microbiology. 156: 967–974. doi:10.1099/mic.0.034736-0. PMID 20007648. 

External links[edit]