Isopropylmalic acid

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Isopropylmalic acid
2-Isopropylmalic acid.svg
2-Isopropylmalic acid
3-Isopropylmalic acid.svg
3-Isopropylmalic acid
Names
IUPAC names
3-Isopropylmalic acid
2-Hydroxy-3-isopropylsuccinic acid
Other names
Isopropylmalate
Identifiers
3D model (JSmol)
ChemSpider
Properties
C7H12O5
Molar mass 176.17 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Isopropylmalic acid (isopropylmalate) is an intermediate in the biosynthesis of leucine, synthesized from oxoisovalerate by 2-isopropylmalate synthase and converted into isopropyl-3-oxosuccinate by 3-isopropylmalate dehydrogenase. Two isomers are important, the 2- and 3-isopropyl derivatives, and these are interconverted by isopropylmalate dehydratase.