(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase
Identifiers
EC number 3.1.3.52
CAS number 88086-29-7&title= 87244-20-0, 88086-29-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase (EC 3.1.3.52, branched-chain oxo-acid dehydrogenase phosphatase, branched-chain 2-keto acid dehydrogenase phosphatase, branched-chain alpha-keto acid dehydrogenase phosphatase, BCKDH, [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase, [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphate phosphohydrolase) is an enzyme with systematic name (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphate phosphohydrolase.[1][2] This enzyme catalyses the following chemical reaction

[3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H2O [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] + phosphate

This mitochondrial enzyme is associated with the 3-methyl-2-oxobutanoate dehydrogenase complex.

References[edit]

  1. ^ Fatania, H.R.; Patston, P.A.; Randle, P.J. (1983). "Dephosphorylation and reactivation of phosphorylated purified ox-kidney branched-chain dehydrogenase complex by co-purified phosphatase". FEBS Lett. 158: 234–238. doi:10.1016/0014-5793(83)80585-7. PMID 6307746. 
  2. ^ Reed, L.J.; Damuni, Z.; Merryfield, M.L. (1985). "Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation". Curr. Top. Cell. Regul. 27: 41–49. PMID 3004826. 

External links[edit]