Dammarenediol II synthase

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Dammarenediol II synthase
Identifiers
EC number 4.2.1.125
CAS number 189354-84-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Dammarenediol II synthase (EC 4.2.1.125, dammarenediol synthase, 2,3-oxidosqualene (20S)-dammarenediol cyclase, DDS, (S)-squalene-2,3-epoxide hydro-lyase (dammarenediol-II forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (dammarenediol-II forming).[1][2] This enzyme catalyses the following chemical reaction

dammarenediol II (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

The reaction occurs in the reverse direction.

References[edit]

  1. ^ Tansakul, P.; Shibuya, M.; Kushiro, T.; Ebizuka, Y. (2006). "Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng". FEBS Lett. 580: 5143–5149. doi:10.1016/j.febslet.2006.08.044. PMID 16962103. 
  2. ^ Han, J.Y.; Kwon, Y.S.; Yang, D.C.; Jung, Y.R.; Choi, Y.E. (2006). "Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng". Plant Cell Physiol. 47: 1653–1662. doi:10.1093/pcp/pcl032. PMID 17088293. 

External links[edit]