Lupan-3beta,20-diol synthase

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Lupan-3beta,20-diol synthase
Identifiers
EC number 4.2.1.128
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Lupan-3beta,20-diol synthase (EC 4.2.1.128, LUP1 (gene)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming).[1][2] This enzyme catalyses the following chemical reaction

lupan-3beta,20-diol (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

The reaction occurs in the reverse direction.

References[edit]

  1. ^ Segura, M.J.; Meyer, M.M.; Matsuda, S.P. (2000). "Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol". Org. Lett. 2: 2257–2259. doi:10.1021/ol006016b. PMID 10930257. 
  2. ^ Kushiro, T.; Hoshino, M.; Tsutsumi, T.; Kawai, K.; Shiro, M.; Shibuya, M.; Ebizuka, Y. (2006). "Stereochemical course in water addition during LUP1-catalyzed triterpene cyclization". Org. Lett. 8: 5589–5592. doi:10.1021/ol062310d. PMID 17107079. 

External links[edit]