Cycloartenol synthase

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cycloartenol synthase
Identifiers
EC number 5.4.99.8
CAS number 9075-25-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a cycloartenol synthase (EC 5.4.99.8) is an enzyme that catalyzes the chemical reaction

(S)-2,3-epoxysqualene cycloartenol

Hence, this enzyme has one substrate, (S)-2,3-epoxysqualene, and one product, cycloartenol.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups, the systematic name of this enzyme class is (S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming). Other names in common use include 2,3-epoxysqualene cycloartenol-cyclase, squalene-2,3-epoxide-cycloartenol cyclase, 2,3-epoxysqualene cycloartenol-cyclase, 2,3-epoxysqualene-cycloartenol cyclase, and 2,3-oxidosqualene-cycloartenol cyclase. This enzyme participates in biosynthesis of steroids.

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