(3S,6E)-nerolidol synthase

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(3S,6E)-nerolidol synthase
EC number
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(3S,6E)-nerolidol synthase (EC, (E)-nerolidol synthase, nerolidol synthase, (3S)-(E)-nerolidol synthase, FaNES1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((3S,6E)-nerolidol-forming) .[1][2][3][4] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O (3S,6E)-nerolidol + diphosphate

The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene.


  1. ^ Aharoni, A.; Giri, A.P.; Verstappen, F.W.; Bertea, C.M.; Sevenier, R.; Sun, Z.; Jongsma, M.A.; Schwab, W.; Bouwmeester, H.J. (2004). "Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species". Plant Cell. 16: 3110–3131. doi:10.1105/tpc.104.023895. PMC 527202Freely accessible. PMID 15522848. 
  2. ^ Bouwmeester, H.J.; Verstappen, F.W.; Posthumus, M.A.; Dicke, M. (1999). "Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis". Plant Physiol. 121: 173–180. doi:10.1104/pp.121.1.173. PMC 59365Freely accessible. PMID 10482672. 
  3. ^ Degenhardt, J.; Gershenzon, J. (2000). "Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis". Planta. 210: 815–822. doi:10.1007/s004250050684. PMID 10805454. 
  4. ^ Arimura, G.; Garms, S.; Maffei, M.; Bossi, S.; Schulze, B.; Leitner, M.; Mithofer, A.; Boland, W. (2008). "Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling". Planta. 227: 453–464. doi:10.1007/s00425-007-0631-y. PMC 2756395Freely accessible. PMID 17924138. 

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