(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing)

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing)
EC number
CAS number 137010-34-5
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) (EC, phellandrene synthase, (−)-beta-phellandrene synthase, (−)-(4S)-beta-phellandrene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing; (4S)-beta-phellandrene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

geranyl diphosphate (4S)-beta-phellandrene + diphosphate

This enzyme requires ion Mn2+.


  1. ^ Savage, T.J.; Hatch, M.W.; Croteau, R. (1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". J. Biol. Chem. 269 (6): 4012–4020. PMID 8307957. 
  2. ^ Bohlmann, J.; Phillips, M.; Ramachandiran, V.; Katoh, S.; Croteau, R. (1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Arch. Biochem. Biophys. 368: 232–243. doi:10.1006/abbi.1999.1332. PMID 10441373. 
  3. ^ Wagschal, K.; Savage, T.J.; Croteau, R. (1991). "Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases". Tetrahedron. 31: 5933–5944. doi:10.1016/s0040-4020(01)86486-3. 
  4. ^ LaFever, R.E.; Croteau, R. (1993). "Hydride shifts in the biosynthesis of the p-menthane monoterpenes α-terpinene, γ-terpinene, and β-phellandrene". Arch. Biochem. Biophys. 301: 361–366. doi:10.1006/abbi.1993.1156. PMID 8460944. 

External links[edit]