(6-4)DNA photolyase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
(6-4)DNA photolyase
Identifiers
EC number 4.1.99.13
CAS number 37290-70-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(6-4)DNA photolyase (EC 4.1.99.13, DNA photolyase, H64PRH, NF-10, phr (6-4), PL-(6-4), OtCPF1, (6-4) PHR, At64PHR) is an enzyme with systematic name (6-4) photoproduct pyrimidine-lyase.[1][2] This enzyme catalyses the following chemical reaction

(6-4) photoproduct (in DNA) 2 pyrimidine residues (in DNA)

This enzyme is a flavoprotein.

References[edit]

  1. ^ Hitomi K, DiTacchio L, Arvai AS, Yamamoto J, Kim ST, Todo T, Tainer JA, Iwai S, Panda S, Getzoff ED (April 2009). "Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes". Proceedings of the National Academy of Sciences of the United States of America. 106 (17): 6962–7. doi:10.1073/pnas.0809180106. PMC 2678464Freely accessible. PMID 19359474. 
  2. ^ Schleicher E, Hitomi K, Kay CW, Getzoff ED, Todo T, Weber S (February 2007). "Electron nuclear double resonance differentiates complementary roles for active site histidines in (6-4) photolyase". The Journal of Biological Chemistry. 282 (7): 4738–47. doi:10.1074/jbc.m604734200. PMID 17164245. 

External links[edit]