Colneleate synthase

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Colneleate synthase
Identifiers
EC number 4.2.1.121
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Colneleate synthase (EC 4.2.1.121, 9-divinyl ether synthase, 9-DES, CYP74D, CYP74D1, CYP74 cytochrome P-450, DES1) is an enzyme with systematic name (8E)-9-((1E,3E)-nona-1,3-dien-1-yloxy)non-8-enoate synthase.[1][2][3][4] This enzyme catalyses the following chemical reaction

(9S,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate (8E)-9-[(1E,3Z)-nona-1,3-dien-1-yloxy]non-8-enoate + H2O

This enzyme is a heme-thiolate protein (P450).

References[edit]

  1. ^ Stumpe, M.; Kandzia, R.; Gobel, C.; Rosahl, S.; Feussner, I. (2001). "A pathogen-inducible divinyl ether synthase (CYP74D) from elicitor-treated potato suspension cells". FEBS Lett. 507: 371–376. doi:10.1016/s0014-5793(01)03019-8. PMID 11696374. 
  2. ^ Itoh, A.; Howe, G.A. (2001). "Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450". J. Biol. Chem. 276: 3620–3627. doi:10.1074/jbc.m008964200. PMID 11060314. 
  3. ^ Fammartino, A.; Cardinale, F.; Gobel, C.; Mene-Saffrane, L.; Fournier, J.; Feussner, I.; Esquerre-Tugaye, M.T. (2007). "Characterization of a divinyl ether biosynthetic pathway specifically associated with pathogenesis in tobacco". Plant Physiol. 143: 378–388. doi:10.1104/pp.106.087304. PMC 1761965Freely accessible. PMID 17085514. 
  4. ^ Hamberg, M. (2005). "Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids". FEBS J. 272: 736–743. doi:10.1111/j.1742-4658.2004.04510.x. PMID 15670154. 

External links[edit]