(Pyruvate, phosphate dikinase)-phosphate phosphotransferase

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(Pyruvate, phosphate dikinase)-phosphate phosphotransferase
EC number
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(Pyruvate, phosphate dikinase)-phosphate phosphotransferase (EC, PPDK regulatory protein, pyruvate, phosphate dikinase regulatory protein, bifunctional dikinase regulatory protein, PDRP1 (gene)) is an enzyme with systematic name (pyruvate, phosphate dikinase) phosphate:phosphate phosphotransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

[pyruvate, phosphate dikinase] phosphate + phosphate [pyruvate, phosphate dikinase] + diphosphate

The enzyme from the plants maize and arabidopsis is bifunctional and also catalyses the phosphorylation of pyruvate.


  1. ^ Burnell, J.N.; Hatch, M.D. (1984). "Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase". Arch. Biochem. Biophys. 231: 175–182. doi:10.1016/0003-9861(84)90375-8. PMID 6326674. 
  2. ^ Burnell, J.N.; Hatch, M.D. (1985). "Regulation of C4 photosynthesis: purification and properties of the protein catalyzing ADP-mediated inactivation and Pi-mediated activation of pyruvate,Pi dikinase". Arch. Biochem. Biophys. 237: 490–503. doi:10.1016/0003-9861(85)90302-9. PMID 2983615. 
  3. ^ Chastain, C.J.; Botschner, M.; Harrington, G.E.; Thompson, B.J.; Mills, S.E.; Sarath, G.; Chollet, R. (2000). "Further analysis of maize C4 pyruvate,orthophosphate dikinase phosphorylation by its bifunctional regulatory protein using selective substitutions of the regulatory Thr-456 and catalytic His-458 residues". Arch. Biochem. Biophys. 375: 165–170. doi:10.1006/abbi.1999.1651. PMID 10683263. 
  4. ^ Burnell, J.N.; Chastain, C.J. (2006). "Cloning and expression of maize-leaf pyruvate, Pi dikinase regulatory protein gene". Biochem. Biophys. Res. Commun. 345: 675–680. doi:10.1016/j.bbrc.2006.04.150. PMID 16696949. 
  5. ^ Chastain, C.J.; Xu, W.; Parsley, K.; Sarath, G.; Hibberd, J.M.; Chollet, R. (2008). "The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure". Plant J. 53: 854–863. doi:10.1111/j.1365-313x.2007.03366.x. PMID 17996018. 

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