Maleate hydratase

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maleate hydratase
Identifiers
EC number 4.2.1.31
CAS number 37290-71-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a maleate hydratase (EC 4.2.1.31) is an enzyme that catalyzes the chemical reaction

(R)-malate maleate + H2O

Hence, this enzyme has one substrate, (R)-malate, and two products, maleate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds, the systematic name of this enzyme class is (R)-malate hydro-lyase (maleate-forming). Other names in common use include D-malate hydro-lyase, malease, and (R)-malate hydro-lyase, this enzyme participates in butanoate metabolism.

References[edit]

  • Britten JS, Morell H, Taggart JV (1969). "Anion activation of maleate hydratase". Biochim. Biophys. Acta. 185 (1): 220–7. doi:10.1016/0005-2744(69)90296-4. PMID 5796106. 
  • SACKS W, JENSEN CO (1951). "Malease, a hydrase from corn kernels". J. Biol. Chem. 192 (1): 231–6. PMID 14917669.