(R)-amidase

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(R)-amidase
Identifiers
EC number 3.5.1.100
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(R)-amidase (EC 3.5.1.100, R-stereospecific amidase, R-amidase) is an enzyme with systematic name (R)-piperazine-2-carboxamide amidohydrolase.[1] This enzyme catalyses the following chemical reaction

(1) (R)-piperazine-2-carboxamide + H2O (R)-piperazine-2-carboxylic acid + NH3
(2) beta-alaninamide + H2O beta-alanine + NH3

This enzyme also hydrolyses (R)-piperidine-3-carboxamide to (R)-piperidine-3-carboxylic acid and NH3.

References[edit]

  1. ^ Komeda, H.; Harada, H.; Washika, S.; Sakamoto, T.; Ueda, M.; Asano, Y. (2004). "A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide". Eur. J. Biochem. 271: 1580–1590. doi:10.1111/j.1432-1033.2004.04069.x. PMID 15066183. 

External links[edit]