3-(imidazol-5-yl)lactate dehydrogenase

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3-(imidazol-5-yl)lactate dehydrogenase
Identifiers
EC number 1.1.1.111
CAS number 37250-42-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 3-(imidazol-5-yl)lactate dehydrogenase (EC 1.1.1.111) is an enzyme that catalyzes the chemical reaction

(S)-3-(imidazol-5-yl)lactate + NAD(P)+ 3-(imidazol-5-yl)pyruvate + NAD(P)H + H+

The 3 substrates of this enzyme are (S)-3-(imidazol-5-yl)lactate, NAD+, and NADP+, whereas its 4 products are 3-(imidazol-5-yl)pyruvate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase. This enzyme is also called imidazol-5-yl lactate dehydrogenase.

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