4-hydroxymandelate oxidase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
4-hydroxymandelate oxidase
Identifiers
EC number 1.1.3.19
CAS number 60976-30-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 4-hydroxymandelate oxidase (EC 1.1.3.19) is an enzyme that catalyzes the chemical reaction

(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 4-hydroxybenzaldehyde + CO2 + H2O2

Thus, the two substrates of this enzyme are (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate and O2, whereas its 3 products are 4-hydroxybenzaldehyde, CO2, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor, the systematic name of this enzyme class is (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase. This enzyme is also called L-4-hydroxymandelate oxidase (decarboxylating). It has 2 cofactors: FAD, and Manganese.

References[edit]