(S)-N-acetyl-1-phenylethylamine hydrolase

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(S)-N-acetyl-1-phenylethylamine hydrolase
Identifiers
EC number 3.5.1.85
CAS number 192230-94-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a (S)-N-acetyl-1-phenylethylamine hydrolase (EC 3.5.1.85) is an enzyme that catalyzes the chemical reaction

N-acetylphenylethylamine + H2O phenylethylamine + acetate

Thus, the two substrates of this enzyme are N-acetylphenylethylamine and H2O, whereas its two products are phenylethylamine and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides, the systematic name of this enzyme class is (S)-N-acetylphenylethylamine:H2O hydrolase. At least one compound, Phenylmethanesulfonylfluoride is known to inhibit this enzyme.

References[edit]

  • Brunella A, Graf M, Kittelmann M, Lauma K, Ghisalba O (1997). "Production, purification, and characterization of a highly enantioselective (S)-N-acetyl-1-phenylethyl amidohydrolase from Rhodococcus". Appl. Microbiol. Biotechnol. 47 (5): 515–520. doi:10.1007/s002530050965.