Lactate aldolase

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lactate aldolase
Identifiers
EC number 4.1.2.36
CAS number 110777-33-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a lactate aldolase (EC 4.1.2.36) is an enzyme that catalyzes the chemical reaction

(S)-lactate formate + acetaldehyde

Hence, this enzyme has one substrate, (S)-lactate, and two products, formate and acetaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-lactate acetaldehyde-lyase (formate-forming). Other names in common use include lactate synthase, and (S)-lactate acetaldehyde-lyase. This enzyme participates in pyruvate metabolism.

References[edit]

  • Gulyi MF, Silonova NV (1987). "[Various metabolic reactions of formate in animal tissues]". Ukr. Biokhim. Zh. 59 (4): 29–35. PMID 3629727.