L-proline amide hydrolase

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L-proline amide hydrolase
Identifiers
EC number 3.5.1.101
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

L-proline amide hydrolase (EC 3.5.1.101, S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase, LaaA, L-amino acid amidase) is an enzyme with systematic name (S)-piperidine-2-carboxamide amidohydrolase.[1] This enzyme catalyses the following chemical reaction

(1) (S)-piperidine-2-carboxamide + H2O (S)-piperidine-2-carboxylic acid + NH3
(2) L-prolinamide + H2O L-proline + NH3

References[edit]

  1. ^ Komeda, H.; Harada, H.; Washika, S.; Sakamoto, T.; Ueda, M.; Asano, Y. (2004). "S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase". Eur. J. Biochem. 271: 1465–1475. doi:10.1111/j.1432-1033.2004.04056.x. PMID 15066172. 

External links[edit]