D(-)-tartrate dehydratase

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D(−)-tartrate dehydratase
Identifiers
EC number 4.2.1.81
CAS number 82532-88-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a D(−)-tartrate dehydratase (EC 4.2.1.81) is an enzyme that catalyzes the chemical reaction

(S,S)-tartrate oxaloacetate + H2O

Hence, this enzyme has one substrate, (S,S)-tartrate, and two products, oxaloacetate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds, the systematic name of this enzyme class is (S,S)-tartrate hydro-lyase (oxaloacetate-forming). Other names in common use include D-tartrate dehydratase, and (S,S)-tartrate hydro-lyase, it has 2 cofactors: iron, and Manganese.

Structural studies[edit]

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2DW6 and 2DW7.

References[edit]