Indoleacetaldoxime dehydratase

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indoleacetaldoxime dehydratase
Identifiers
EC number 4.99.1.6
CAS number 9024-27-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an indoleacetaldoxime dehydratase (EC 4.99.1.6) is an enzyme that catalyzes the chemical reaction

(indol-3-yl)acetaldehyde oxime (indol-3-yl)acetonitrile + H2O

Hence, this enzyme has one substrate, (indol-3-yl)acetaldehyde oxime, and two products, (indol-3-yl)acetonitrile and H2O.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is (indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]. Other names in common use include indoleacetaldoxime hydro-lyase, 3-indoleacetaldoxime hydro-lyase, indole-3-acetaldoxime hydro-lyase, indole-3-acetaldehyde-oxime hydro-lyase, and (indol-3-yl)acetaldehyde-oxime hydro-lyase. This enzyme participates in cyanoamino acid metabolism.

References[edit]

  • KUMAR SA, MAHADEVAN S (1963). "3-INDOLEACETALDOXIME HYDRO-LYASE: A PYRIDOXAL-5'-PHOSPHATE ACTIVATED ENZYME". Arch. Biochem. Biophys. 103 (3): 516–8. doi:10.1016/0003-9861(63)90446-6. PMID 14099566. 
  • Mahadevan S (1963). "Conversion of 3-indoleacetoxime to 3-indoleacetonitrile by plants". Arch. Biochem. Biophys. 100 (3): 557–558. doi:10.1016/0003-9861(63)90127-9.