Indolelactate dehydrogenase

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indolelactate dehydrogenase
Identifiers
EC number 1.1.1.110
CAS number 37250-41-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an indolelactate dehydrogenase (EC 1.1.1.110) is an enzyme that catalyzes the chemical reaction

(indol-3-yl)lactate + NAD+ (indol-3-yl)pyruvate + NADH + H+

Thus, the two substrates of this enzyme are (indol-3-yl)lactate and NAD+, whereas its 3 products are (indol-3-yl)pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (indol-3-yl)lactate:NAD+ oxidoreductase. This enzyme is also called indolelactate:NAD+ oxidoreductase. This enzyme participates in tryptophan metabolism.

References[edit]

  • Jean M, DeMoss RD (1968). "Indolelactate dehydrogenase from Clostridium sporogenes". Can. J. Microbiol. 14 (4): 429–35. doi:10.1139/m68-068. PMID 4384683.