(S,S)-butanediol dehydrogenase

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(S,S)-butanediol dehydrogenase
Identifiers
EC number1.1.1.76
CAS number37250-14-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a (S,S)-butanediol dehydrogenase (EC 1.1.1.76) is an enzyme that catalyzes the chemical reaction

(S,S)-butane-2,3-diol + NAD+ acetoin + NADH + H+

Thus, the two substrates of this enzyme are (S,S)-butane-2,3-diol and NAD+, whereas its 3 products are acetoin, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S,S)-butane-2,3-diol:NAD+ oxidoreductase. Other names in common use include L-butanediol dehydrogenase, L-BDH, and L(+)-2,3-butanediol dehydrogenase (L-acetoin forming). This enzyme participates in butanoic acid metabolism.

References[edit]

  • Taylor MB; Juni E (1960). "Stereoisomeric specificities of 2,3-butanediol dehydrogenase". Biochim. Biophys. Acta. 39 (3): 448&ndash, 457. doi:10.1016/0006-3002(60)90197-9. PMID 13837186.