Quinalizarin

From Wikipedia, the free encyclopedia
  (Redirected from 1,2,5,8-Tetrahydroxyanthraquinone)
Jump to: navigation, search
Quinalizarin
Skeletal formula of quinalizarin
Ball-and-stick model
Names
IUPAC name
1,2,5,8-Tetrahydroxyanthracene-9,10-dione
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.001.243
Properties
C14H8O6
Molar mass 272.21 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Quinalizarin or 1,2,5,8-tetrahydroxyanthraquinone is an organic compound with formula C
14
H
8
O
6
. It is one of many tetrahydroxyanthraquinone isomers, formally derived from anthraquinone by replacement of four hydrogen atoms by hydroxyl (OH) groups.

Quinalizarin is an inhibitor of the enzyme protein kinase CK2, it is more potent and selective than emodin.[1]

See also[edit]

References[edit]

  1. ^ Cozza, G.; Mazzorana, M.; Papinutto, E.; Bain, J.; Elliott, M.; di Maira, G.; Gianoncelli, A.; Pagano, M. A.; Sarno, S.; Ruzzene, M.; Battistutta, R.; Meggio, F.; Moro, S.; Zagotto, G.; Pinna, L. A. (2009). "Quinalizarin as a Potent, Selective and Cell-Permeable Inhibitor of Protein Kinase CK2" (pdf). The Biochemical Journal. 421 (3): 387–395. doi:10.1042/BJ20090069. PMID 19432557.