Alpha-santonin 1,2-reductase

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alpha-santonin 1,2-reductase
Identifiers
EC number 1.3.1.47
CAS number 111070-23-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an alpha-santonin 1,2-reductase (EC 1.3.1.47) is an enzyme that catalyzes the chemical reaction

1,2-dihydrosantonin + NAD(P)+ alpha-santonin + NAD(P)H + H+

The 3 substrates of this enzyme are 1,2-dihydrosantonin, NAD+, and NADP+, whereas its 4 products are alpha-santonin, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor, the systematic name of this enzyme class is 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase.

References[edit]

  • Naik U, Mavuinkurve S (1987). "alpha-Santonin 1,2-reductase and its role in the formation of dihydrosantonin and lumisantonin by Pseudomonas cichorii S". Can. J. Microbiol. 33 (8): 658–62. doi:10.1139/m87-115. PMID 3690421.