6-aminohexanoate-cyclic-dimer hydrolase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
6-aminohexanoate-cyclic-dimer hydrolase
Identifiers
EC number 3.5.2.12
CAS number 60976-29-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) is an enzyme that catalyzes the chemical reaction

1,8-diazacyclotetradecane-2,9-dione + H2O N-(6-aminohexanoyl)-6-aminohexanoate

Thus, the two substrates of this enzyme are 1,8-diazacyclotetradecane-2,9-dione and H2O, whereas its product is N-(6-aminohexanoyl)-6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase.

References[edit]

  • Kinoshita S, Negoro S, Muramatsu M, Bisaria VS, Sawada S, Okada H (1977). "6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI74". Eur. J. Biochem. 80 (2): 489–95. doi:10.1111/j.1432-1033.1977.tb11904.x. PMID 923591.